Growth Hormone Withdrawal in Mid-Puberty: No Impact on Near Adult Height in Adolescents With Transient Idiopathic GHD

In adolescents with transient IIGHD, rhGH treatment can be stopped at mid-puberty. These findings support reducing rhGH treatment duration, lowering patient burden and healthcare costs.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2025-11-14
DOI
https://doi.org/10.1210/clinem/dgaf626
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
Field-Weighted Citation Impact
0.00

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article

Growth Hormone Withdrawal in Mid-Puberty: No Impact on Near Adult Height in Adolescents With Transient Idiopathic GHD

Annemieke M. Boot, Theo Sas, Edgar van Mil, Daniëlle C M van der Kaay et al.
The Journal of Clinical Endocrinology & Metabolism
Growth Hormone and Insulin-like Growth Factors
article

Growth Hormone Withdrawal in Mid-Puberty: No Impact on Near Adult Height in Adolescents With Transient Idiopathic GHD

Annemieke M. Boot, Theo Sas, Edgar van Mil, Daniëlle C M van der Kaay, Saartje Straetemans, A S Paul van Trotsenburg, Josine C. van der Heyden, Christiaan de Bruin, D Schött, Robbert N.H. Touwslager, Martijn J.J. Finken, Boudewijn Bakker, Erica L T van den Akker, Jan M. Wit, Edmond H.H.M. Rings, Anita Hokken-Koelega, Vera van Tellingen, Joeri Vliegenthart, Petra van Setten, H.J. van der Kamp, Paul G. Voorhoeve
article en

Abstract

In adolescents with transient IIGHD, rhGH treatment can be stopped at mid-puberty. These findings support reducing rhGH treatment duration, lowering patient burden and healthcare costs.

The Journal of Clinical Endocrinology & Metabolism
Leiden University (NL), University Medical Center Groningen (NL), Radboud University Nijmegen (NL), Leiden University Medical Center (NL), Maastricht University Medical Centre (NL), Catharina Ziekenhuis (NL), Erasmus MC (NL), Radboud University Medical Center (NL), Sint Franciscus Gasthuis (NL), Emma Kinderziekenhuis (NL), Reinier de Graaf Hospital (NL), St. Antonius Ziekenhuis (NL), Dutch CAA Foundation (NL), Canisius-Wilhelmina Ziekenhuis (NL), Amalia Kinderziekenhuis (NL), Beatrix Kinderziekenhuis (NL), Willem-Alexander Kinderziekenhuis (NL), Zuyderland Medisch Centrum (NL), Erasmus MC - Sophia Children’s Hospital (NL), Franciscus Vlietland (NL), Foundation for Growth Science (JP), Jeroen Bosch Ziekenhuis (NL), Hersenstichting (NL), Wilhelmina Children's Hospital (NL), University of Amsterdam (NL)
ZonMw
Openalex Percentile: Top 54%
Growth Hormone and Insulin-like Growth Factors
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