Effect of mavacamten and disopyramide on left ventricular mechanical dispersion and life-threatening arrhythmia in obstructive hypertrophic cardiomyopathy
Mavacamten, but not disopyramide, decreased LVMD, GWW, and increased GWE in obstructive HCM. LVMD <72 ms at follow-up is promising for assessing the risk for life-threatening ventricular arrhythmias.
Authors
- Benay Özbay (ORCID: https://orcid.org/0000-0002-2039-5770)
- William E. Katz (ORCID: https://orcid.org/0000-0003-2490-8833)
- N.A. Mark Estes (ORCID: https://orcid.org/0000-0002-5461-7247)
- Leyla Elif Sade (ORCID: https://orcid.org/0000-0003-3737-8595)
- Genise Renee Green
- Timothy C. Wong (ORCID: https://orcid.org/0000-0002-1045-2698)
- Matthew S. Suffoletto
- Elizabeth Luttner
Institutions
- University of Pittsburgh (US)
- UPMC Health System (US)
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Imaging
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1093/ehjci/jeaf318
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00