Tegoprazan Versus Proton Pump Inhibitors for Erosive Esophagitis: A Meta‐Analysis of Noninferiority Randomized Controlled Trials

Tegoprazan shows comparable efficacy and safety to standard PPIs for treating EE. While healing rates were slightly higher, particularly with the 100 mg dose, the differences were not statistically significant. Tegoprazan may be a suitable alternative for patients intolerant to PPIs, though larger, long-term, multiethnic studies are warranted to confirm these findings and assess patient-centered outcomes.

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Publication Details

Journal
JGH Open
Published
2025-11-01
DOI
https://doi.org/10.1002/jgh3.70298
Primary Topic
Eosinophilic Esophagitis
Type
article
Field-Weighted Citation Impact
0.00
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article

Tegoprazan Versus Proton Pump Inhibitors for Erosive Esophagitis: A Meta‐Analysis of Noninferiority Randomized Controlled Trials

Qasim Mehmood, Azka Ijaz, Zahin Shahriar, Muhammad Imaz Bhatti et al.
JGH Open
Eosinophilic Esophagitis
article

Tegoprazan Versus Proton Pump Inhibitors for Erosive Esophagitis: A Meta‐Analysis of Noninferiority Randomized Controlled Trials

Qasim Mehmood, Azka Ijaz, Zahin Shahriar, Muhammad Imaz Bhatti, Muhammad Safiullah, Ishmal Fatima Shahid
article en

Abstract

Tegoprazan shows comparable efficacy and safety to standard PPIs for treating EE. While healing rates were slightly higher, particularly with the 100 mg dose, the differences were not statistically significant. Tegoprazan may be a suitable alternative for patients intolerant to PPIs, though larger, long-term, multiethnic studies are warranted to confirm these findings and assess patient-centered outcomes.

JGH OpenVol. 9(11)
King Edward Medical University (PK), Dhaka Medical College and Hospital (BD)
Openalex Percentile: Top 47%
Eosinophilic Esophagitis
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