Surgical Management of Pediatric Primary Hyperoxaluria Type 1: An Eight‐Patient Case Series in the Pre‐ <scp>siRNA</scp> Era

This case series illustrates the surgical complexity and multidisciplinary coordination required in pediatric PH1 management and supports the role of seqLKT with conduit-based hepatic artery reconstruction and intensive dialysis bridging as effective approaches in selected patients, particularly in settings without access to gene-targeted therapy.

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Publication Details

Journal
Pediatric Transplantation
Published
2025-11-14
DOI
https://doi.org/10.1111/petr.70225
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Surgical Management of Pediatric Primary Hyperoxaluria Type 1: An Eight‐Patient Case Series in the Pre‐ siRNA Era

Héctor Melín‐Aldana, Alexandre Darani, Riccardo Antonio Superina, Gal Finer et al.
Pediatric Transplantation
Kidney Stones and Urolithiasis Treatments
article

Surgical Management of Pediatric Primary Hyperoxaluria Type 1: An Eight‐Patient Case Series in the Pre‐ siRNA Era

Héctor Melín‐Aldana, Alexandre Darani, Riccardo Antonio Superina, Gal Finer, Sarah Ward, Matthew G. Switalski
article en

Abstract

This case series illustrates the surgical complexity and multidisciplinary coordination required in pediatric PH1 management and supports the role of seqLKT with conduit-based hepatic artery reconstruction and intensive dialysis bridging as effective approaches in selected patients, particularly in settings without access to gene-targeted therapy.

Pediatric TransplantationVol. 29(8)
Northwestern University (US), Lurie Children's Hospital (US), Children's Hospital at Montefiore (US)
Openalex Percentile: Top 50%
Kidney Stones and Urolithiasis Treatments
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