Computed Tomography-Guided Versus Fluoroscopy-Guided Celiac Plexus Neurolysis for Pancreatic Cancer Pain: A Novel Comparative Study Integrating Pain Phenotyping and Functional Outcomes

Both CT and fluoroscopy-guided CPN provide effective pain relief in pancreatic cancer. However, CT-guided CPN is associated with significantly greater pain reduction, especially in patients with neuropathic pain features, lower complication rates and better functional outcomes. Pain phenotyping using LANSS enhances procedural decision-making and supports a personalised approach to palliative care in pancreatic malignancy.