Facial Proliferative Pyoderma Gangrenosum Mimicking Infectious Dermatoses

The authors declare no conflicts of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request. Figure S1: Histopathological images of the skin lesion (A–C). (A) Low-power view shows marked epidermal hyperplasia with irregular elongation of the rete ridges and dense inflammatory cell infiltration in the dermis. (B, C) Higher magnification demonstrates dense mixed inflammatory infiltrates composed predominantly of neutrophils forming microabscesses. Granulomatous inflammation, consisting of lymphocytes, histiocytes, plasma cells, and scattered eosinophils, is observed surrounding the abscess area. No obvious microorganisms are identified on routine H&E staining (H&E staining; A, ×10; B, ×40; C, ×100). Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Publication Details

Journal
The Journal of Dermatology
Published
2025-11-14
DOI
https://doi.org/10.1111/1346-8138.70023
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
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article

Facial Proliferative Pyoderma Gangrenosum Mimicking Infectious Dermatoses

Wei-Hong Wu, Jia Liao, Xueyi Huang, Min Tan
The Journal of Dermatology
Autoimmune and Inflammatory Disorders
article

Facial Proliferative Pyoderma Gangrenosum Mimicking Infectious Dermatoses

Wei-Hong Wu, Jia Liao, Xueyi Huang, Min Tan
article en

Abstract

The authors declare no conflicts of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request. Figure S1: Histopathological images of the skin lesion (A–C). (A) Low-power view shows marked epidermal hyperplasia with irregular elongation of the rete ridges and dense inflammatory cell infiltration in the dermis. (B, C) Higher magnification demonstrates dense mixed inflammatory infiltrates composed predominantly of neutrophils forming microabscesses. Granulomatous inflammation, consisting of lymphocytes, histiocytes, plasma cells, and scattered eosinophils, is observed surrounding the abscess area. No obvious microorganisms are identified on routine H&E staining (H&E staining; A, ×10; B, ×40; C, ×100). Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

The Journal of DermatologyVol. 52(12)
Zhongshan City Second People's Hospital (CN)
Openalex Percentile: Top 55%
Autoimmune and Inflammatory Disorders
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