Assessing the interaction of the UCP system and fatty acids on epicardial adipose tissue mitochondrial respiration
This study emphasizes the important bioenergetic differences between EAT and SAT, which are crucial in the context of the local cardiomyocyte metabolism, as well as the impact of UCP1 inhibition in EAT. A deeper understanding of the unique characteristics of EAT and its metabolic micro-environment may provide valuable insights into the cardiovascular disease pathologies.
Authors
- Aryane Cruz Oliveira Pinho (ORCID: https://orcid.org/0000-0003-2235-2237)
- David Prieto‐Merino (ORCID: https://orcid.org/0000-0001-5001-0061)
- Ana Burgeiro (ORCID: https://orcid.org/0000-0001-8467-3840)
- Diana Santos (ORCID: https://orcid.org/0000-0002-9292-5961)
- Teresa Cunha‐Oliveira (ORCID: https://orcid.org/0000-0002-7382-0339)
- Eugénia Carvalho (ORCID: https://orcid.org/0000-0001-6264-3632)
- Cândida Dias (ORCID: https://orcid.org/0000-0003-4744-9254)
- João Laranjinha (ORCID: https://orcid.org/0000-0003-4370-5177)
- António Canotilho
- Ana Catarina R. G. Fonseca
- Gonçalo Coutinho (ORCID: https://orcid.org/0000-0003-2724-4905)
- Pedro Antunes (ORCID: https://orcid.org/0000-0001-6910-8456)
- M. Antunes (ORCID: https://orcid.org/0009-0003-3573-1241)
Institutions
- Instituto Politécnico de Leiria (PT)
- Hospitais da Universidade de Coimbra (PT)
- Instituto Superior de Línguas e Administração (PT)
- University of Coimbra (PT)
Publication Details
- Journal
- European Journal of Clinical Investigation
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1111/eci.70149
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação para a Ciência e a Tecnologia
- European Regional Development Fund