Tranexamic acid in multiply injured patients–the independent risk of thromboembolic complications with repeated dosing: retrospective analysis based on the TraumaRegister DGU®
In our study we report on an associated risk of thromboembolic events in multiply injured patients with every single time tranexamic acid was administered in our study. Thus, before a repetitive dose of tranexamic acid is administered checking for indication is advised and especially in multiply injured patients receiving repeated administrations of TXA starting a thromboprophylaxis, as soon as possible after the traumatic bleeding disorder is controlled, is important.
Authors
- Ferdinand Christian Wagner (ORCID: https://orcid.org/0000-0003-0842-9445)
- Hagen Schmal (ORCID: https://orcid.org/0000-0002-8801-2385)
- Tim Kirchner
- Rolf L. Lefering (ORCID: https://orcid.org/0000-0002-0141-1747)
- Jörg Bayer (ORCID: https://orcid.org/0000-0001-5446-6840)
- Lisa Bode
Institutions
- Witten/Herdecke University (DE)
- University Medical Center Freiburg (DE)
- Odense University Hospital (DK)
- Schwarzwald-Baar Klinikum (DE)
Publication Details
- Journal
- Scandinavian Journal of Trauma Resuscitation and Emergency Medicine
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1186/s13049-025-01512-1
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00