Tranexamic acid in multiply injured patients–the independent risk of thromboembolic complications with repeated dosing: retrospective analysis based on the TraumaRegister DGU®

In our study we report on an associated risk of thromboembolic events in multiply injured patients with every single time tranexamic acid was administered in our study. Thus, before a repetitive dose of tranexamic acid is administered checking for indication is advised and especially in multiply injured patients receiving repeated administrations of TXA starting a thromboprophylaxis, as soon as possible after the traumatic bleeding disorder is controlled, is important.

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Publication Details

Journal
Scandinavian Journal of Trauma Resuscitation and Emergency Medicine
Published
2025-11-15
DOI
https://doi.org/10.1186/s13049-025-01512-1
Primary Topic
Blood transfusion and management
Type
article
Field-Weighted Citation Impact
0.00
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article

Tranexamic acid in multiply injured patients–the independent risk of thromboembolic complications with repeated dosing: retrospective analysis based on the TraumaRegister DGU®

Ferdinand Christian Wagner, Hagen Schmal, Tim Kirchner, Rolf L. Lefering et al.
Scandinavian Journal of Trauma Resuscitation and Emergency Medicine
Blood transfusion and management
article

Tranexamic acid in multiply injured patients–the independent risk of thromboembolic complications with repeated dosing: retrospective analysis based on the TraumaRegister DGU®

Ferdinand Christian Wagner, Hagen Schmal, Tim Kirchner, Rolf L. Lefering, Jörg Bayer, Lisa Bode
article en

Abstract

In our study we report on an associated risk of thromboembolic events in multiply injured patients with every single time tranexamic acid was administered in our study. Thus, before a repetitive dose of tranexamic acid is administered checking for indication is advised and especially in multiply injured patients receiving repeated administrations of TXA starting a thromboprophylaxis, as soon as possible after the traumatic bleeding disorder is controlled, is important.

Scandinavian Journal of Trauma Resuscitation and Emergency MedicineVol. 33(1)
Witten/Herdecke University (DE), University Medical Center Freiburg (DE), Odense University Hospital (DK), Schwarzwald-Baar Klinikum (DE)
Openalex Percentile: Top 65%
Blood transfusion and management
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