Quantitative analysis of chest computed tomography in alpha-1-antitrypsin deficiency
The study provides new insights into the distribution of emphysema, with lobar-specific quantitative analysis challenging the existing paradigm that emphysema in severe AATD is most pronounced in the lower lobes.
Authors
- Katharina Buschulte (ORCID: https://orcid.org/0000-0002-7598-5276)
- Mark Oliver Wielpütz (ORCID: https://orcid.org/0000-0001-6962-037X)
- Oliver Weinheimer (ORCID: https://orcid.org/0000-0002-9507-076X)
- Felix Herth (ORCID: https://orcid.org/0000-0002-7638-2506)
- Julia Dorothea Michels-Zetsche (ORCID: https://orcid.org/0000-0002-7006-7054)
- Claus Peter Heußel (ORCID: https://orcid.org/0000-0001-5809-5733)
- Franziska Christina Trudzinski (ORCID: https://orcid.org/0000-0002-0980-7586)
- Sebastian Fähndrich (ORCID: https://orcid.org/0000-0001-9910-2063)
- Arved Bischoff (ORCID: https://orcid.org/0000-0002-7147-2414)
- Hilal Ersöz
- Philipp Höger (ORCID: https://orcid.org/0009-0006-6637-9166)
- Ralf Eberhardt
- Arturo Olivares Rivera
- Johanna Benholz
Institutions
- Heidelberg University (DE)
- Universitätsmedizin Greifswald (DE)
- University Medical Center Freiburg (DE)
- University Hospital Heidelberg (DE)
- Universität Greifswald (DE)
- Frauenklinik Heidelberg (DE)
- German Center for Lung Research (DE)
- Asklepios Klinik Barmbek (DE)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1186/s12931-025-03413-4
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00