<scp> <i>GBA1</i> </scp> Variants with Unknown Classification Are Modest Contributors to Parkinson's Disease Susceptibility
Unknown GBA1 variants may be considered provisionally in clinical trials if also classified as VUS, likely pathogenic, or pathogenic per ACMG criteria. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Yoomin Lee
- Sitki Cem Parlar (ORCID: https://orcid.org/0009-0003-9026-114X)
- Ziv Gan‐Or (ORCID: https://orcid.org/0000-0003-0332-234X)
Institutions
- Montreal Neurological Institute and Hospital (CA)
- McGill University (CA)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1002/mds.70127
- Primary Topic
- Lysosomal Storage Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Michael J. Fox Foundation for Parkinson's Research
- Canadian Institutes of Health Research
- Fonds de Recherche du Québec - Santé