Seizure outcomes of laser interstitial thermal therapy ( <scp>LITT</scp> ) for drug‐resistant extratemporal epilepsy

In our study of subjects with ETLE who underwent LITT for DRE, 78% achieved >90% reduction of seizure frequency from baseline and 78% of patients achieved a successful Engel Class I outcome after a mean follow-up of 35 months. We demonstrate LITT ablation is a safe and effective method of treatment for drug-resistant ETLE and may be considered even with heterogeneous etiologies or prior surgeries.

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Publication Details

Journal
Epileptic Disorders
Published
2025-11-15
DOI
https://doi.org/10.1002/epd2.70129
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
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Seizure outcomes of laser interstitial thermal therapy ( LITT ) for drug‐resistant extratemporal epilepsy

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Epileptic Disorders
Epilepsy research and treatment
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Seizure outcomes of laser interstitial thermal therapy ( LITT ) for drug‐resistant extratemporal epilepsy

Jessica Falco‐Walter, Jaimie M. Henderson, David Arnold Purger, Gavin Touponse, Allan Wang, Vivek Buch, Casey H. Halpern, Scheherazade Le
article en

Abstract

In our study of subjects with ETLE who underwent LITT for DRE, 78% achieved >90% reduction of seizure frequency from baseline and 78% of patients achieved a successful Engel Class I outcome after a mean follow-up of 35 months. We demonstrate LITT ablation is a safe and effective method of treatment for drug-resistant ETLE and may be considered even with heterogeneous etiologies or prior surgeries.

Epileptic DisordersVol. 28(1)
University of California, Los Angeles (US), Stanford Medicine (US), Neurological Surgery (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US), University of Pennsylvania (US), Stanford University (US)
Openalex Percentile: Top 59%
Epilepsy research and treatment
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