Refractory Systemic Sclerosis–Related Digital Ulcer Successfully Treated With Hyperbaric Oxygen Therapy: A Case Report and Literature Review

<i>Case. </i> A 24-year-old woman with newly diagnosed limited cutaneous systemic sclerosis (SSc) presented with 2 ulcers with gangrene of the right fourth digit, which did not respond to nifedipine and tadalafil. Initial treatment with aspirin, nitroglycerin patches, narcotic analgesics, and empirical antibiotics for concomitant soft tissue infection proved inadequate, as the ulcers continued to enlarge.

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Publication Details

Journal
The Journal of Rheumatology
Published
2025-11-15
DOI
https://doi.org/10.3899/jrheum.2025-0651
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Refractory Systemic Sclerosis–Related Digital Ulcer Successfully Treated With Hyperbaric Oxygen Therapy: A Case Report and Literature Review

Sindhu R. Johnson, Huda Alfaris, Rita Katznelson
The Journal of Rheumatology
Systemic Sclerosis and Related Diseases
article

Refractory Systemic Sclerosis–Related Digital Ulcer Successfully Treated With Hyperbaric Oxygen Therapy: A Case Report and Literature Review

Sindhu R. Johnson, Huda Alfaris, Rita Katznelson
article en

Abstract

<i>Case. </i> A 24-year-old woman with newly diagnosed limited cutaneous systemic sclerosis (SSc) presented with 2 ulcers with gangrene of the right fourth digit, which did not respond to nifedipine and tadalafil. Initial treatment with aspirin, nitroglycerin patches, narcotic analgesics, and empirical antibiotics for concomitant soft tissue infection proved inadequate, as the ulcers continued to enlarge.

The Journal of Rheumatology
Mount Sinai Hospital (CA), University Health Network (CA), Riyadh Armed Forces Hospital (SA), University of Toronto (CA), Toronto Western Hospital (CA)
Openalex Percentile: Top 52%
Systemic Sclerosis and Related Diseases
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