Refractory Systemic Sclerosis–Related Digital Ulcer Successfully Treated With Hyperbaric Oxygen Therapy: A Case Report and Literature Review
<i>Case. </i> A 24-year-old woman with newly diagnosed limited cutaneous systemic sclerosis (SSc) presented with 2 ulcers with gangrene of the right fourth digit, which did not respond to nifedipine and tadalafil. Initial treatment with aspirin, nitroglycerin patches, narcotic analgesics, and empirical antibiotics for concomitant soft tissue infection proved inadequate, as the ulcers continued to enlarge.
Authors
- Sindhu R. Johnson (ORCID: https://orcid.org/0000-0003-0591-2976)
- Huda Alfaris (ORCID: https://orcid.org/0000-0002-1253-1453)
- Rita Katznelson (ORCID: https://orcid.org/0000-0003-2992-7435)
Institutions
- Mount Sinai Hospital (CA)
- University Health Network (CA)
- Riyadh Armed Forces Hospital (SA)
- University of Toronto (CA)
- Toronto Western Hospital (CA)
Publication Details
- Journal
- The Journal of Rheumatology
- Published
- 2025-11-15
- DOI
- https://doi.org/10.3899/jrheum.2025-0651
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00