SPIO-enhanced MRI for sentinel lymph node mapping in oral cancer: a prospective feasibility study
The use of superparamagnetic iron oxide (SPIO)-enhanced MRI in head and neck cancer is underassessed. SPIO-enhanced MRI detects nodal drainage patterns comparably to SPECT/CT. SPIO-enhanced MRI does not discriminate lymph node metastases from false positives.
Authors
- Adriana C. H. van Engen–van Grunsven (ORCID: https://orcid.org/0000-0002-3154-3601)
- Sjoert Pegge (ORCID: https://orcid.org/0000-0001-9314-6137)
- Robert Paul Takes (ORCID: https://orcid.org/0000-0003-4784-0499)
- Tim Dijkema
- Gijs T. N. Heldens (ORCID: https://orcid.org/0000-0003-4912-7806)
- Tom W. J. Scheenen (ORCID: https://orcid.org/0000-0002-4468-1480)
- Willem L. J. Weijs
- Patrik Zámecnik (ORCID: https://orcid.org/0000-0001-8658-0242)
- Daphne A. J. J. Driessen (ORCID: https://orcid.org/0000-0002-7675-3987)
- Anne I.J. Arens (ORCID: https://orcid.org/0000-0001-7066-5372)
- J.H.A.M. Kaanders
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1186/s41747-025-00636-4
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Radboud Institute for Health Sciences