Neurodevelopmental Disorders and L-carnosine: A Clinical Perspective

Neurodevelopmental disorders (NDDs) affect approximately 15% of children and adolescents worldwide.Neurodevelopmental disorders, including attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), pose significant challenges in diagnosis, care, and treatment.L-carnosine, a naturally occurring dipeptide with antioxidant and neuroprotective properties, has shown therapeutic potential in managing NDDs.The complex interplay of genetic, environmental, and epigenetic factors in NDDs necessitates a comprehensive treatment approach.L-carnosine, a naturally occurring dipeptide with antioxidant, anti-inflammatory, and neuroprotective properties, has shown therapeutic potential in managing NDDs.Clinical studies have demonstrated that L-carnosine supplementation can improve behavioral symptoms, cognitive function, and social communication in children with ADHD and ASD.This review explores the potential therapeutic effects of L-carnosine on NDDs and implications for clinical practice.The findings suggest that L-carnosine could be a valuable complementary treatment option in the comprehensive management of NDDs, offering a promising avenue for improving the lives of affected individuals.

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Publication Details

Journal
Journal of Academy of Pediatric Neurology
Published
2025-11-14
DOI
https://doi.org/10.5005/jaopn-11028-0019
Primary Topic
Biochemical effects in animals
Type
article
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article

Neurodevelopmental Disorders and L-carnosine: A Clinical Perspective

Anisha Doshi, Aaditi Phadke, Neel Patel, Shailesh Pallewar et al.
Journal of Academy of Pediatric Neurology
Biochemical effects in animals
article

Neurodevelopmental Disorders and L-carnosine: A Clinical Perspective

Anisha Doshi, Aaditi Phadke, Neel Patel, Shailesh Pallewar, Ashwin Kotamkar, Prabhojit Mohanty, Anjalika Atrey, Puja Kapoor, Pramod Jog, Amit Qamra
article en

Abstract

Neurodevelopmental disorders (NDDs) affect approximately 15% of children and adolescents worldwide.Neurodevelopmental disorders, including attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), pose significant challenges in diagnosis, care, and treatment.L-carnosine, a naturally occurring dipeptide with antioxidant and neuroprotective properties, has shown therapeutic potential in managing NDDs.The complex interplay of genetic, environmental, and epigenetic factors in NDDs necessitates a comprehensive treatment approach.L-carnosine, a naturally occurring dipeptide with antioxidant, anti-inflammatory, and neuroprotective properties, has shown therapeutic potential in managing NDDs.Clinical studies have demonstrated that L-carnosine supplementation can improve behavioral symptoms, cognitive function, and social communication in children with ADHD and ASD.This review explores the potential therapeutic effects of L-carnosine on NDDs and implications for clinical practice.The findings suggest that L-carnosine could be a valuable complementary treatment option in the comprehensive management of NDDs, offering a promising avenue for improving the lives of affected individuals.

Journal of Academy of Pediatric NeurologyVol. 2(1)
Openalex Percentile: Top 58%
Biochemical effects in animals
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