Neurodevelopmental Disorders and L-carnosine: A Clinical Perspective
Neurodevelopmental disorders (NDDs) affect approximately 15% of children and adolescents worldwide.Neurodevelopmental disorders, including attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), pose significant challenges in diagnosis, care, and treatment.L-carnosine, a naturally occurring dipeptide with antioxidant and neuroprotective properties, has shown therapeutic potential in managing NDDs.The complex interplay of genetic, environmental, and epigenetic factors in NDDs necessitates a comprehensive treatment approach.L-carnosine, a naturally occurring dipeptide with antioxidant, anti-inflammatory, and neuroprotective properties, has shown therapeutic potential in managing NDDs.Clinical studies have demonstrated that L-carnosine supplementation can improve behavioral symptoms, cognitive function, and social communication in children with ADHD and ASD.This review explores the potential therapeutic effects of L-carnosine on NDDs and implications for clinical practice.The findings suggest that L-carnosine could be a valuable complementary treatment option in the comprehensive management of NDDs, offering a promising avenue for improving the lives of affected individuals.
Authors
- Anisha Doshi (ORCID: https://orcid.org/0000-0001-6699-8668)
- Aaditi Phadke
- Neel Patel
- Shailesh Pallewar
- Ashwin Kotamkar
- Prabhojit Mohanty
- Anjalika Atrey
- Puja Kapoor
- Pramod Jog
- Amit Qamra
Publication Details
- Journal
- Journal of Academy of Pediatric Neurology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.5005/jaopn-11028-0019
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00