Could Transforming Growth Factor Beta and Target MicroRNA Dysregulation Serve as Biomarkers of Symptom Severity in Patients With Obsessive‐Compulsive Disorder?
Altered TGF-β and miRNA-132-3p levels may contribute to OCD pathophysiology by affecting BDNF regulation, inflammatory responses (Th1/Th2, Th17/Treg balance) and synaptic plasticity-related genes.
Authors
- Sinan Altunöz (ORCID: https://orcid.org/0000-0001-6043-2882)
- Ayla Solmaz Avcıkurt (ORCID: https://orcid.org/0000-0002-1521-7152)
- Nazan Dolapoğlu (ORCID: https://orcid.org/0000-0003-1400-7580)
- Özgür Baykan (ORCID: https://orcid.org/0000-0001-8551-6900)
- Hilmi Bolat (ORCID: https://orcid.org/0000-0001-6574-8149)
- Tunay Karlıdere (ORCID: https://orcid.org/0000-0003-2143-0651)
Institutions
- Balıkesir University (TR)
Publication Details
- Journal
- International Journal of Developmental Neuroscience
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/jdn.70070
- Citations
- 1
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.31