B‐Type Natriuretic Peptides Levels in Patients With Beta‐Thalassemia Major and Correlations With Biomarkers: A Systematic Review and Meta‐Analysis
This systematic review provides evidence that beta-thalassemia is associated with high levels of B-type natriuretic peptides, which highlight the high risk of cardiovascular complications in this patient population. The significantly elevated levels of both molecules and their identified correlations emphasize clinical utility of them as markers of early myocardial stress and subclinical heart disease in beta-thalassemia.
Authors
- Hamdy H. Hassan (ORCID: https://orcid.org/0000-0001-7274-9414)
- Abdelrahim Osman Mohamed (ORCID: https://orcid.org/0000-0003-0840-1637)
- Ola Ahmed (ORCID: https://orcid.org/0000-0002-8778-6979)
- Sagad Omer Obeid Mohamed (ORCID: https://orcid.org/0000-0003-0597-2397)
- Elsara Mohamed Ali Mirghani
- Nada Omar
- Mohamed S. K. Salih
- Mohammed Y. K. Makki (ORCID: https://orcid.org/0009-0006-0960-9308)
- Esraa Mohammed
- Esraa M. A. Garalnabi
Institutions
- University of Khartoum (SD)
- Alzaiem Alazhari University (SD)
- Al-Neelain University (SD)
- Harlem Hospital Center (US)
- Newcastle upon Tyne Hospital (GB)
Publication Details
- Journal
- Health Science Reports
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/hsr2.71493
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00