Causal Relationship Between Inflammatory Bowel Disease and Neuropsychiatric Disorders: A Bidirectional Mendelian Randomization Study
Our results support potential causal relationships between IBD (including its subtypes CD and UC) and several neuropsychiatric disorders, reinforcing the gut-brain axis concept and enhancing our understanding of extra-intestinal manifestations of IBD and neuropsychiatric manifestations in the context of IBD.
Authors
- J. Deng (ORCID: https://orcid.org/0009-0004-4874-652X)
- Liping Gong
- Jian Lei (ORCID: https://orcid.org/0000-0002-5214-4730)
- Shan Wei (ORCID: https://orcid.org/0000-0001-6211-7368)
Institutions
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- Hunan Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/brb3.71046
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00