Primary antiphospholipid syndrome and the kidney: biopsy-proven insights from two referral Italian centres
Intra-renal involvement in PAPS is rare but heterogeneous, encompassing both vascular and glomerular pathologies. These findings support the need for heightened renal surveillance in PAPS, even in the absence of classic thrombotic manifestations, and highlight the importance of histologic assessment to guide tailored therapy. From a nephrologist's perspective, routine screening for aPL in glomerular disease assessment may be relevant, particularly by providing prognostic value for subsequent aPL-related events.
Authors
- Mattia Zappa
- Dario Roccatello (ORCID: https://orcid.org/0000-0002-4419-6813)
- Micaela Fredi (ORCID: https://orcid.org/0000-0002-6511-4936)
- Savino Sciascia (ORCID: https://orcid.org/0000-0003-1266-9441)
- Franco Franceschini (ORCID: https://orcid.org/0000-0003-3678-6124)
- Federica Mescia (ORCID: https://orcid.org/0000-0002-2759-4027)
- Cecilia Nalli (ORCID: https://orcid.org/0000-0003-2514-9891)
- Federico Alberici (ORCID: https://orcid.org/0000-0002-1686-5709)
- Liala Moschetti (ORCID: https://orcid.org/0000-0003-4976-9550)
- Ilaria Cavazzana (ORCID: https://orcid.org/0000-0002-2757-7120)
- Massimo Radin (ORCID: https://orcid.org/0000-0003-1941-2606)
- Laura Andréoli (ORCID: https://orcid.org/0000-0002-9107-3218)
- Anǵela Tincani (ORCID: https://orcid.org/0000-0003-4355-9333)
- Stefania Affatato
Institutions
- Surgical Specialties (Canada) (CA)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Ospedale San Giovanni Bosco (IT)
- University of Brescia (IT)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1093/rheumatology/keaf593
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00