Aqueous humour biomarker profiles in angle-closure glaucoma: systematic review and meta-analysis
Several biomarkers were elevated in the aqueous humour of patients with ACG compared to cataract controls, providing insights into the molecular mechanisms of angle closure and elevated intraocular pressure. Future studies should focus on the potential for biomarker-driven diagnostics and longitudinal designs to further advance personalized management strategies.
Authors
- Andrew Mihalache (ORCID: https://orcid.org/0000-0002-2692-0759)
- Ryan S. Huang (ORCID: https://orcid.org/0000-0002-3404-5376)
- David J. Mathew (ORCID: https://orcid.org/0000-0001-8488-2060)
- Michael Balas (ORCID: https://orcid.org/0000-0002-5948-0331)
Institutions
- University Health Network (CA)
- University of Toronto (CA)
- Toronto Rehabilitation Institute (CA)
- Krembil Research Institute
Publication Details
- Journal
- Canadian Journal of Ophthalmology
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jcjo.2025.09.021
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00