Exploring Endoplasmic Reticulum Stress-Related Genes in Cartilage Defects: Implications for Diagnosis and Therapy
This study reveals the key roles of ER stress and immune dysregulation in CDs. Moreover, the ERSRDEG-based diagnostic model provides preliminary bioinformatics evidence and potential molecular indicators for targeted diagnostics and therapies.
Authors
- Guowei Zeng (ORCID: https://orcid.org/0000-0003-1530-3883)
- Kai Luo (ORCID: https://orcid.org/0000-0002-1345-8243)
- Haoqi Cai
- Bozhong Shi (ORCID: https://orcid.org/0000-0003-3794-6601)
- Xiaoyang Zhang (ORCID: https://orcid.org/0000-0002-0031-0290)
- Cong Li (ORCID: https://orcid.org/0000-0003-2588-4781)
- Bo Chen (ORCID: https://orcid.org/0000-0002-9926-4377)
- Jinghao Zheng (ORCID: https://orcid.org/0000-0001-7459-6730)
- Linjian Huang (ORCID: https://orcid.org/0000-0002-1446-5998)
- Xiaomin He (ORCID: https://orcid.org/0000-0002-6079-1014)
Institutions
- Shanghai Children's Medical Center (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-11-14
- DOI
- https://doi.org/10.2174/0113862073441646251107115725
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00