A sex‐informed transcriptomic prognostic score for gynecologic cancers: Multiplatform validation and spatial characterization
This sex-informed, spatially validated score provides a reproducible and biologically interpretable framework for transcriptomic risk stratification in gynecologic cancers. By capturing immune-evasive and aggressive tumor states, it might inform biomarker-guided clinical trials and support context-appropriate implementation of precision oncology strategies.
Authors
- Ignacio Wichmann (ORCID: https://orcid.org/0000-0002-1115-2937)
- Fernán Gómez‐Valenzuela (ORCID: https://orcid.org/0000-0001-6889-976X)
- Sumie Kato
- Mauricio A. Cuello (ORCID: https://orcid.org/0000-0003-2812-0015)
- Carolina Ibáñez (ORCID: https://orcid.org/0000-0001-6982-7928)
Institutions
- Universidad Mayor (CL)
- Pontificia Universidad Católica de Chile (CL)
- Hospital Clínico de la Universidad Católica (CL)
- Stanford University (US)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1002/ijgo.70650
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00