Correlation of gut microbiota metabolite trimethylamine N-oxide with inflammatory levels and osteoporosis in patients with diabetic nephropathy
Inflammatory and bone metabolic levels in patients with DN were found to be associated with the gut microbiota-derived metabolite TMAO. Elevated TMAO levels may mediate inflammatory responses and bone metabolism disorders in patients with DN, thereby contributing to the progression of systemic inflammation and OP.
Authors
- Zhanglei Pan
- Mingqiang Li (ORCID: https://orcid.org/0000-0002-5178-4138)
- Lingyu Xue
- Jing Zhang (ORCID: https://orcid.org/0000-0002-4148-6268)
- Yan‐Ping Shi (ORCID: https://orcid.org/0000-0001-6517-9556)
Institutions
- Affiliated Hospital of Taishan Medical University (CN)
- Taian City Central Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-11-14
- DOI
- https://doi.org/10.4239/wjd.v16.i11.109919
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81