Antiarrhythmic drugs for cardiac arrest with a shockable rhythm and their effect on outcomes – A systematic review with meta-analysis

Evidence supporting the use of any antiarrhythmic drugs during CPR remains limited and is partly inconclusive. For the effect on survival to hospital discharge, a statistically significant difference was only found favouring the administration of lidocaine compared to no lidocaine. Further research with improved trial design and into novel drug options should be conducted.

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Publication Details

Journal
EP Europace
Published
2025-11-07
DOI
https://doi.org/10.1093/europace/euaf289
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
Field-Weighted Citation Impact
0.00
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article

Antiarrhythmic drugs for cardiac arrest with a shockable rhythm and their effect on outcomes – A systematic review with meta-analysis

Alexander Niessner, Samuel Tobias Sossalla, Brigitte Wildner, Roman Brock et al.
EP Europace
Cardiac Arrest and Resuscitation
article

Antiarrhythmic drugs for cardiac arrest with a shockable rhythm and their effect on outcomes – A systematic review with meta-analysis

Alexander Niessner, Samuel Tobias Sossalla, Brigitte Wildner, Roman Brock, Karina Tapinova, Patrick Sulzgruber, Mario Krammel, Sebastian Schnaubelt, Christoph Veigl, Andrea Kornfehl
article en

Abstract

Evidence supporting the use of any antiarrhythmic drugs during CPR remains limited and is partly inconclusive. For the effect on survival to hospital discharge, a statistically significant difference was only found favouring the administration of lidocaine compared to no lidocaine. Further research with improved trial design and into novel drug options should be conducted.

EP EuropaceVol. 27(12)
Danube Private University (AT), Fachhochschule Wiener Neustadt (AT), University Clinic of Traumatology (AT), Health Awareness (United States) (US), Kerckhoff Klinik (DE), Medical University of Vienna (AT)
Openalex Percentile: Top 50%
Cardiac Arrest and Resuscitation
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Antiarrhythmic drugs for cardiac arrest with a shockable rhythm and their effect on outcomes – A systematic review with meta-analysis — Alexander Niessner, Samuel Tobias Sossalla, et al. · EP Europace (2025) | TGRS Research Map | TGRS