Phytochemical and nanoparticle-based therapeutic potential of Sphaeranthus indicus against hepatocellular carcinoma via cryptomeridiol targeting
Si extract, cryptomeridiol, and SiAgNPs are well-characterized, biologically active agents that induce apoptosis and inhibit HepG2 proliferation. These findings highlight cryptomeridiol as a potent phytochemical scaffold and demonstrate the translational potential of combining phytochemicals with nanotechnology for hepatocellular carcinoma therapy through the <i>in-vitro model</i>.
Authors
- Abhinandan Patil (ORCID: https://orcid.org/0000-0002-1154-0753)
- Garima Chawla
- Somnath D. Bhinge (ORCID: https://orcid.org/0000-0002-5959-5833)
- Ritika Ravindra Konduskar
- Yash Bhagavan Yadav
Institutions
- Krishna Institute of Medical Sciences (IN)
- Krishna Institute of Medical Sciences Deemed University (IN)
- D.Y. Patil Education Society (IN)
- Bharati Vidyapeeth (Deemed to be University) (IN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.3389/fonc.2025.1691905
- Primary Topic
- Synthesis and bioactivity of alkaloids
- Type
- article
- Field-Weighted Citation Impact
- 0.00