Posterior interosseous nerve compressive neuropathy due to gouty tophi: a case report and literature review

Gout is a metabolic disorder characterized by the deposition of monosodium urate crystals in joints and soft tissues, which may lead to the formation of gouty tophi in chronic cases. We report a rare case of posterior interosseous nerve palsy caused by compression from gouty tophi in the elbow region. The patient underwent surgical decompression and excision of the tophi, with subsequent full recovery of finger extension. This case highlights that gouty tophi, though rare, can be a treatable cause of posterior interosseous nerve neuropathy. Tophaceous gout should be included in the differential diagnosis when evaluating unexplained motor deficits, especially in patients with a history of gout or risk factors for hyperuricemia.

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Publication Details

Journal
Archives of Hand and Microsurgery
Published
2025-11-14
DOI
https://doi.org/10.12790/ahm.25.0012
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
0.00
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article

Posterior interosseous nerve compressive neuropathy due to gouty tophi: a case report and literature review

Hyo-Kon Kim, Sung-Han Ha, Jin Sik Park, W. P. Andrew Lee
Archives of Hand and Microsurgery
Gout, Hyperuricemia, Uric Acid
article

Posterior interosseous nerve compressive neuropathy due to gouty tophi: a case report and literature review

Hyo-Kon Kim, Sung-Han Ha, Jin Sik Park, W. P. Andrew Lee
article en

Abstract

Gout is a metabolic disorder characterized by the deposition of monosodium urate crystals in joints and soft tissues, which may lead to the formation of gouty tophi in chronic cases. We report a rare case of posterior interosseous nerve palsy caused by compression from gouty tophi in the elbow region. The patient underwent surgical decompression and excision of the tophi, with subsequent full recovery of finger extension. This case highlights that gouty tophi, though rare, can be a treatable cause of posterior interosseous nerve neuropathy. Tophaceous gout should be included in the differential diagnosis when evaluating unexplained motor deficits, especially in patients with a history of gout or risk factors for hyperuricemia.

Archives of Hand and MicrosurgeryVol. 30(4)
Kyungpook National University Hospital (KR), Daegu Fatima Hospital (KR)
Openalex Percentile: Top 59%
Gout, Hyperuricemia, Uric Acid
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