Prediagnosis diabetes, life-course body mass index and physical activity, and pancreatic cancer survival in older adults
Prediagnosis diabetes was associated with reduced PDAC survival. Life-course BMI and leisure-time physical activity were not associated with PDAC survival overall. Higher early-adulthood and older-adulthood BMIs were associated with poorer survival among patients with unstaged disease; however, stage is an important determinant of survival that we were unable to control for in this group.
Authors
- Hyokyoung Grace Hong (ORCID: https://orcid.org/0000-0002-4280-6243)
- Noah C. Peeri (ORCID: https://orcid.org/0000-0003-4278-650X)
- Charles Edwards Matthews (ORCID: https://orcid.org/0000-0001-8037-3103)
- Pedro F. Saint‐Maurice (ORCID: https://orcid.org/0000-0002-8752-2340)
- Rachael Z. Stolzenberg‐Solomon (ORCID: https://orcid.org/0000-0003-3698-7006)
Institutions
- Champalimaud Foundation (PT)
- Memorial Sloan Kettering Cancer Center (US)
- National Cancer Institute (US)
- Division of Cancer Epidemiology and Genetics
Publication Details
- Journal
- JNCI Cancer Spectrum
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1093/jncics/pkaf110
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Cancer Institute