Purple Light-Promoted Ferrier Photobromination of <i>O</i> -Benzoylated Carbohydrates in Benzotrifluoride

Our laboratory has previously reported on a contemporary Ferrier photobromination which circumvents critical limitations of the original reaction. The new conditions provide highly efficient and scalable routes to <i>O</i>-acetylated 5-<i>C</i>-bromosugars but cannot be used to access <i>O</i>-benzoylated derivatives. Herein, we show that the scope of the Ferrier photobromination can be expanded to encompass important <i>O</i>-benzoylated carbohydrates by a simple but effective modification of the reaction conditions. This advance importantly paves the way for improved syntheses of glycosidase inhibitors and rare L-hexoses.