Intra-operative physiologic interventions associated with postoperative neurological complications in neonates and infants

In this secondary analysis of neonates and infants undergoing cardiac and noncardiac procedures, we found a higher rate of neurologic complications compared to adult populations undergoing noncardiac surgery. There was no association between unexpected intra-operative instability of systemic homeostasis necessitating a corrective action and subsequent neurologic complications; however, these findings do not necessarily indicate the absence of any effect of physiological disturbances on neurologic outcomes.

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Publication Details

Journal
European Journal of Anaesthesiology
Published
2025-11-11
DOI
https://doi.org/10.1097/eja.0000000000002308
Primary Topic
Anesthesia and Neurotoxicity Research
Type
article
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article

Intra-operative physiologic interventions associated with postoperative neurological complications in neonates and infants

Nicola Disma, Sanne E. Hoeks, Robert Jan Stolker, Jurgen C. de Graaff et al.
European Journal of Anaesthesiology
Anesthesia and Neurotoxicity Research
article

Intra-operative physiologic interventions associated with postoperative neurological complications in neonates and infants

Nicola Disma, Sanne E. Hoeks, Robert Jan Stolker, Jurgen C. de Graaff, László Vutskits, Virginia Tangel
article en

Abstract

In this secondary analysis of neonates and infants undergoing cardiac and noncardiac procedures, we found a higher rate of neurologic complications compared to adult populations undergoing noncardiac surgery. There was no association between unexpected intra-operative instability of systemic homeostasis necessitating a corrective action and subsequent neurologic complications; however, these findings do not necessarily indicate the absence of any effect of physiological disturbances on neurologic outcomes.

European Journal of AnaesthesiologyVol. 43(4)
Apple (Israel) (IL), Cornell University (US), Erasmus MC (NL), Geneva College (US), Erasmus University Rotterdam (NL)
Openalex Percentile: Top 62%
Anesthesia and Neurotoxicity Research
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