Adaptive Ketogenic–Mediterranean Protocol (AKMP) in Real Clinical Practice: 14-Week Pre–Post Cohort Study on Glucolipid Markers and Safety
In adults with overweight or obesity, the AKMP was associated with improvements in the glucose-insulin axis, atherogenic profile (RC, TG/HDL-c, TG), and body composition, while maintaining a favorable safety profile. The protocol appears feasible in clinical practice and monitorable with routine laboratory tests, although randomized controlled trials are needed to confirm causality and long-term sustainability.
Authors
- Nadia San Onofre (ORCID: https://orcid.org/0000-0003-1029-0681)
- José M. Soriano (ORCID: https://orcid.org/0000-0003-2846-1311)
- Juan Francisco Merino-Torres (ORCID: https://orcid.org/0000-0002-0191-4504)
- Cayetano García-Gorrita (ORCID: https://orcid.org/0000-0001-6940-7341)
Institutions
- Universitat Oberta de Catalunya (ES)
- Universitat de València (ES)
- Parc Científic de la Universitat de València (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- Instituto de Ciencia de Materiales de Sevilla (ES)
- Instituto de Investigación Sanitaria La Fe (ES)
Publication Details
- Journal
- Nutrients
- Published
- 2025-11-14
- DOI
- https://doi.org/10.3390/nu17223559
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00