Tuberculosis sequelae

A 59-year-old male, a farmer, a chronic alcoholic, presented to the emergency department with complaints of breathing difficulty, cough with expectoration, and fever for the past 3 days. The patient gives a history of tubercular pleural effusion 3 years back, for which he took treatment for 9 months. Laboratory investigations were within normal range. Chest X-ray showed patchy opacities in the bilateral upper lobes and localised left lower pleural calcification. High-resolution computed tomography (HRCT) thorax of the patient showed centrimetric mediastinal lymph nodes, bilateral upper lobe consolidation with cystic bronchiectatic changes, and calcified pleural plaques on the left side, with small hydropneumothorax, with a communicating peripheral bronchus suggestive of bronchopleural fistula. After ruling out active tuberculosis by sputum analysis and bronchoscopy, the patient was referred to the pulmonology department, where he underwent bronchoscopic coil application for bronchopleural fistula closure. The patient was treated with broad-spectrum antibiotics, nutritional support, and physiotherapy. The patient improved symptomatically and is currently on follow-up. Despite efficient treatment modalities, some patients develop consequences. The most common parenchymal sequelae are cavitation, fibrotic bands, aspergilloma, cicatrisation, and end-stage lung disease. The pleural sequelae include chronic empyema, fibrothorax, bronchopleural fistula, and pneumothorax. The airway sequelae include bronchiectasis, tracheobronchial stenosis, and broncholithiasis. The vascular sequelae include pulmonary arteritis, thrombosis, bronchial arteritis, and Rasmussen aneurysm. Early diagnosis and treatment, ensuring treatment adherence, monitoring response to treatment, pulmonary rehabilitation, and regular follow-ups have to be ensured to prevent consequences.

Authors

Institutions

Publication Details

Journal
Pan African Medical Journal
Published
2025-11-10
DOI
https://doi.org/10.11604/pamj.2025.52.100.48609
Primary Topic
Pleural and Pulmonary Diseases
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Tuberculosis sequelae

Ashwin Karnan
Pan African Medical Journal
Pleural and Pulmonary Diseases
article

Tuberculosis sequelae

Ashwin Karnan
article en

Abstract

A 59-year-old male, a farmer, a chronic alcoholic, presented to the emergency department with complaints of breathing difficulty, cough with expectoration, and fever for the past 3 days. The patient gives a history of tubercular pleural effusion 3 years back, for which he took treatment for 9 months. Laboratory investigations were within normal range. Chest X-ray showed patchy opacities in the bilateral upper lobes and localised left lower pleural calcification. High-resolution computed tomography (HRCT) thorax of the patient showed centrimetric mediastinal lymph nodes, bilateral upper lobe consolidation with cystic bronchiectatic changes, and calcified pleural plaques on the left side, with small hydropneumothorax, with a communicating peripheral bronchus suggestive of bronchopleural fistula. After ruling out active tuberculosis by sputum analysis and bronchoscopy, the patient was referred to the pulmonology department, where he underwent bronchoscopic coil application for bronchopleural fistula closure. The patient was treated with broad-spectrum antibiotics, nutritional support, and physiotherapy. The patient improved symptomatically and is currently on follow-up. Despite efficient treatment modalities, some patients develop consequences. The most common parenchymal sequelae are cavitation, fibrotic bands, aspergilloma, cicatrisation, and end-stage lung disease. The pleural sequelae include chronic empyema, fibrothorax, bronchopleural fistula, and pneumothorax. The airway sequelae include bronchiectasis, tracheobronchial stenosis, and broncholithiasis. The vascular sequelae include pulmonary arteritis, thrombosis, bronchial arteritis, and Rasmussen aneurysm. Early diagnosis and treatment, ensuring treatment adherence, monitoring response to treatment, pulmonary rehabilitation, and regular follow-ups have to be ensured to prevent consequences.

Pan African Medical JournalVol. 52
Datta Meghe Institute of Higher Education and Research (IN)
Openalex Percentile: Top 51%
Pleural and Pulmonary Diseases
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Tuberculosis sequelae — Ashwin Karnan · Pan African Medical Journal (2025) | TGRS Research Map | TGRS