Assessment of Guideline-Directed Medical Therapy Optimization Scores and Readmission Risk in Heart Failure With Reduced Ejection Fraction
In this multi-center cohort, OMT and mOMT scores, but not GDMT count or KCMO, were associated with 90-day HF readmissions. Findings highlight the potential utility of simpler GDMT scoring systems while underscoring the need for refined tools incorporating dose intensity, class-specific weighting, and longitudinal therapy to better guide optimization efforts.
Authors
- Le Thanh Hoang Nhat (ORCID: https://orcid.org/0000-0002-3756-7217)
- Jennifer Namba (ORCID: https://orcid.org/0000-0002-4710-593X)
- Scott E. Strome (ORCID: https://orcid.org/0000-0003-0927-8722)
- Jaekyu Shin (ORCID: https://orcid.org/0000-0002-7097-9977)
- Mina D. Fahmy (ORCID: https://orcid.org/0000-0001-5783-6974)
- Zaid Yousif
- B Dang (ORCID: https://orcid.org/0009-0005-2952-8807)
- Christine Cadiz (ORCID: https://orcid.org/0000-0002-3009-5966)
- Tiffany Pon (ORCID: https://orcid.org/0000-0001-6733-3123)
- Yvette Hellier
- Andrew Willeford (ORCID: https://orcid.org/0000-0002-2146-3624)
- Trina Huynh
- Hanna Jensen (ORCID: https://orcid.org/0000-0001-8487-7982)
- M.G. Staskauskas
- Lı Wang (ORCID: https://orcid.org/0000-0003-1688-064X)
- Chigusa Nakamura
- Jethro Pobre
Institutions
- University of California, San Francisco (US)
- University of California, Irvine (US)
- UC San Diego Health System (US)
- Ronald Reagan UCLA Medical Center (US)
- University of California San Diego (US)
- Irvine University (US)
- University of California Davis Medical Center (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1177/10600280251387249
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00