Hepatosplenic abscess due to Burkholderia pseudomallei-a retrospective review of nineteen cases from a tertiary care centre in South India

Spleen and liver are the most commonly affected extrapulmonary visceral organs in melioidosis. We present the clinical features and outcome of nineteen cases of hepatosplenic abscess due to Burkholderia pseudomallei reported between 2015 and 2023. Isolated liver abscess, isolated splenic involvement and concurrent liver and spleen abscess were seen in 5 (26 %), 7 (37 %) and 7 (37 %) patients correspondingly. Honeycomb sign was seen in 10 (83 %) patients with liver abscess. Splenic involvement in the form multiple microabscesses was seen in 4 (29 %) patients and multiple larger discrete and coalescent abscesses in 10 (71 %) patients. Seventeen patients recovered with treatment.

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Journal
Indian Journal of Medical Microbiology
Published
2025-11-01
DOI
https://doi.org/10.1016/j.ijmmb.2025.101007
Primary Topic
Burkholderia infections and melioidosis
Type
article
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article

Hepatosplenic abscess due to Burkholderia pseudomallei-a retrospective review of nineteen cases from a tertiary care centre in South India

V Mangayarkarasi, Shunmuga Sundaram Ponnusamy, Tara Rajendran, Rajalakshmi Preethi G et al.
Indian Journal of Medical Microbiology
Burkholderia infections and melioidosis
article

Hepatosplenic abscess due to Burkholderia pseudomallei-a retrospective review of nineteen cases from a tertiary care centre in South India

V Mangayarkarasi, Shunmuga Sundaram Ponnusamy, Tara Rajendran, Rajalakshmi Preethi G, V. Balaji, G. Vithiya
article en

Abstract

Spleen and liver are the most commonly affected extrapulmonary visceral organs in melioidosis. We present the clinical features and outcome of nineteen cases of hepatosplenic abscess due to Burkholderia pseudomallei reported between 2015 and 2023. Isolated liver abscess, isolated splenic involvement and concurrent liver and spleen abscess were seen in 5 (26 %), 7 (37 %) and 7 (37 %) patients correspondingly. Honeycomb sign was seen in 10 (83 %) patients with liver abscess. Splenic involvement in the form multiple microabscesses was seen in 4 (29 %) patients and multiple larger discrete and coalescent abscesses in 10 (71 %) patients. Seventeen patients recovered with treatment.

Indian Journal of Medical MicrobiologyVol. 58
Indraprastha Apollo Hospitals (IN), Velammal Medical College Hospital and Research Institute (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 55%
Burkholderia infections and melioidosis
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