Clinical Outcomes and Institutional Experience of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer
This study reports real-world clinical outcomes of patients with stage 0-II breast cancer treated with U-HFRT. We observed low rates of acute skin toxicity compared to M-HFRT, confirming its acceptability as a standard regimen for select patients. Longer term follow-up would be necessary to confirm clinical outcomes in terms of both local control and late normal tissue toxicity.
Authors
- Fei‐Fei Liu (ORCID: https://orcid.org/0000-0003-4344-6486)
- Thomas G. Purdie (ORCID: https://orcid.org/0000-0003-4176-8457)
- Rachel Glicksman (ORCID: https://orcid.org/0000-0002-0555-8754)
- Danielle Rodin (ORCID: https://orcid.org/0000-0001-8279-0621)
- Ezra Hahn (ORCID: https://orcid.org/0000-0002-3206-1903)
- Jennifer Croke (ORCID: https://orcid.org/0000-0002-7090-6313)
- Kathy Han (ORCID: https://orcid.org/0000-0001-8439-3929)
- Zeynep Baskurt (ORCID: https://orcid.org/0000-0002-0714-7406)
- Michelle M. Chan (ORCID: https://orcid.org/0000-0001-9451-9716)
- Naghmeh Isfahanian (ORCID: https://orcid.org/0000-0002-0782-4550)
- Anthony Fyles (ORCID: https://orcid.org/0000-0002-3633-2483)
- Anne Koch (ORCID: https://orcid.org/0000-0002-3420-4875)
- Aisling Barry (ORCID: https://orcid.org/0000-0003-1587-669X)
- Joelle Helou
- Hiba Othman (ORCID: https://orcid.org/0009-0005-8156-7889)
Institutions
- University Health Network (CA)
- University of Toronto (CA)
- Princess Margaret Cancer Centre (CA)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1016/j.adro.2025.101948
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00