Bell’s Palsy: Are Anti-virals Required?

Objectives: This study aimed to analyse the demographic profile, associated factors, treatment approaches, and outcomes of patients with Bell’s palsy (BP), and to compare the therapeutic efficacy of steroid monotherapy against combined steroid-antiviral therapy. Methods: Following approval from the institutional ethics committee, this retrospective analysis was carried out in the Department of Otolaryngology between January 2021 and January 2024. Data from 120 patients diagnosed with BP were reviewed. Group 1 ( n = 69) received corticosteroids alone, whereas Group 2 ( n = 51) received a combination of systemic corticosteroids and antiviral medication. Each group was further subdivided based on the time of treatment initiation—within 72 hours or after 72 hours of symptom onset. All patients were assessed before and after therapy using the House–Brackmann grading system. Results: No significant association was found between prognosis and either age or sex. Initiation of treatment within three days of onset was linked to better recovery. Patients treated with a steroid-antiviral combination demonstrated superior outcomes compared to those receiving steroid monotherapy. Conclusion: BP is an acute idiopathic lower motor neuron facial paralysis. Early initiation of combined corticosteroid and antiviral therapy, preferably within 72 hours of onset, is associated with improved recovery outcomes.

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Publication Details

Journal
Apollo Medicine
Published
2025-11-14
DOI
https://doi.org/10.1177/09760016251395364
Primary Topic
Facial Nerve Paralysis Treatment and Research
Type
article
Field-Weighted Citation Impact
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article

Bell’s Palsy: Are Anti-virals Required?

Bashir Ahmad Malik, Majid Ul Islam Masoodi, Asef Wani, Faizah Ashfah Latief Deva
Apollo Medicine
Facial Nerve Paralysis Treatment and Research
article

Bell’s Palsy: Are Anti-virals Required?

Bashir Ahmad Malik, Majid Ul Islam Masoodi, Asef Wani, Faizah Ashfah Latief Deva
article en

Abstract

Objectives: This study aimed to analyse the demographic profile, associated factors, treatment approaches, and outcomes of patients with Bell’s palsy (BP), and to compare the therapeutic efficacy of steroid monotherapy against combined steroid-antiviral therapy. Methods: Following approval from the institutional ethics committee, this retrospective analysis was carried out in the Department of Otolaryngology between January 2021 and January 2024. Data from 120 patients diagnosed with BP were reviewed. Group 1 ( n = 69) received corticosteroids alone, whereas Group 2 ( n = 51) received a combination of systemic corticosteroids and antiviral medication. Each group was further subdivided based on the time of treatment initiation—within 72 hours or after 72 hours of symptom onset. All patients were assessed before and after therapy using the House–Brackmann grading system. Results: No significant association was found between prognosis and either age or sex. Initiation of treatment within three days of onset was linked to better recovery. Patients treated with a steroid-antiviral combination demonstrated superior outcomes compared to those receiving steroid monotherapy. Conclusion: BP is an acute idiopathic lower motor neuron facial paralysis. Early initiation of combined corticosteroid and antiviral therapy, preferably within 72 hours of onset, is associated with improved recovery outcomes.

Apollo Medicine
Sher-i-Kashmir Institute of Medical Sciences (IN)
Openalex Percentile: Top 52%
Facial Nerve Paralysis Treatment and Research
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