Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer
NR suppressed fatty acid metabolism and malignant biological behaviors of CRC cells, which was involved in the inhibition of ADORA3. This study reveals the anticancer activity of NR in CRC, providing experimental evidence for its further development as an adjuvant therapy or chemopreventive agent for CRC.
Authors
- Rongrong Jiang (ORCID: https://orcid.org/0000-0001-5541-6271)
- Hao Wang (ORCID: https://orcid.org/0000-0001-7594-7387)
- Liu C (ORCID: https://orcid.org/0000-0002-2219-1018)
- Fei Chen (ORCID: https://orcid.org/0009-0003-5558-7830)
Institutions
- Linyi City Chinese Medicine Hospital (CN)
- Yantaishan Hospital (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1111/jgh.70165
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00