Performance Characteristics of Anti–Collagen <scp>II</scp> Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis
Anti-Col2 antibodies are neither sensitive nor specific for RP, are detected in the minority of patients with RP, and are detected at similar prevalences across a spectrum of inflammatory diseases with cartilage inflammation. Use of these antibodies to diagnose or monitor RP is not advisable.
Authors
- Claire Stein (ORCID: https://orcid.org/0000-0002-5165-2901)
- Benjamin A. Turturice (ORCID: https://orcid.org/0000-0001-9382-4612)
- Alice Fike (ORCID: https://orcid.org/0000-0003-2597-1981)
- Kaitlin A. Quinn (ORCID: https://orcid.org/0000-0002-5794-194X)
- Marcela A. Ferrada (ORCID: https://orcid.org/0000-0003-3256-3273)
- Peter C. Grayson (ORCID: https://orcid.org/0000-0002-8269-9438)
- Karyssa Stonick
Institutions
- University of Maryland, Baltimore (US)
- National Institutes of Health (US)
- University of Baltimore (US)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1002/acr.25697
- Primary Topic
- Otitis Media and Relapsing Polychondritis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases