Antinuclear Autoantibody‐Negative Systemic Lupus Erythematosus ( <scp>SLE</scp> ): A Reality or Shortcomings of Diagnostics and Interpretation?
This letter highlights the critical need for clinicians to understand antinuclear antibody (ANA) testing methodologies and autoantibody specificities to prevent diagnostic errors and accurately applying classification criteria. Anti-Ro52 is an antinuclear antibody whose detection fulfills the 2019 EULAR/ACR classification entry criterion.
Authors
- Ayman Azhary (ORCID: https://orcid.org/0000-0002-2804-1408)
- Nooh Mohamed Hajhamed (ORCID: https://orcid.org/0009-0003-3717-1815)
- Salahaldeen Ismail (ORCID: https://orcid.org/0000-0001-9991-1573)
Institutions
- Omdurman Islamic University (SD)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/ccr3.71415
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00