Effects of Benzalkonium Chloride, a Preservative in Topical Drugs, on the Barrier Function of Human Corneal Epithelial Cells
Real-time impedance and mitochondrial assessments determine thresholds for BAK toxicity, guiding the development of safer ophthalmic formulations to protect the ocular surface.
Authors
- Xiang Zheng (ORCID: https://orcid.org/0000-0001-7588-825X)
- Miho Nishiyama
- Ahmed S. Ibrahim (ORCID: https://orcid.org/0000-0001-8480-6252)
- Diego G. Ogando (ORCID: https://orcid.org/0000-0002-3632-9954)
- Sangly P. Srinivas (ORCID: https://orcid.org/0000-0002-7528-0735)
- Mohamed Shawky
Institutions
- Damietta University (EG)
- Mansoura University (EG)
- Wayne State University (US)
- Indiana University Bloomington (US)
- Rohto Pharmaceutical (Japan) (JP)
Publication Details
- Journal
- Translational Vision Science & Technology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1167/tvst.14.11.16
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Research to Prevent Blindness
- Wayne State University
- National Institutes of Health