Timing of Intrapartum Antibiotics at Caesarean Section and Risk of Asthma, Eczema and Allergic Rhinitis: Results From a Natural Experiment
This study found no evidence of an association between pre-incision antibiotics for CS and increased risk of asthma, eczema or allergic rhinitis by age 5. These findings contribute to the evidence base informing the optimum timing of maternal antibiotic prophylaxis for CS, balancing risks and benefits to the mother and her child.
Authors
- Sérgio Souza da Cunha (ORCID: https://orcid.org/0000-0002-4926-3827)
- Emily Petherick (ORCID: https://orcid.org/0000-0001-6778-8128)
- Gillian Santorelli (ORCID: https://orcid.org/0000-0003-0427-1783)
- Lucy Pembrey (ORCID: https://orcid.org/0000-0002-0455-7469)
- Neil Pearce (ORCID: https://orcid.org/0000-0002-9938-7852)
- Sam Oddie (ORCID: https://orcid.org/0000-0001-8701-4912)
- John Wright (ORCID: https://orcid.org/0000-0001-9572-7293)
- Amy Hough (ORCID: https://orcid.org/0009-0007-8888-7599)
Institutions
- Loughborough University (GB)
- University of Leicester (GB)
- University Hospitals of Leicester NHS Trust (GB)
- National Institute for Health and Care Research (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Bradford Teaching Hospitals NHS Foundation Trust (GB)
- NIHR Leicester Biomedical Research Centre (GB)
Publication Details
- Journal
- BJOG An International Journal of Obstetrics & Gynaecology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1111/1471-0528.70083
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Bristol
- Health Technology Assessment Programme