Unraveling the Therapeutic Mechanisms of Shanzhen Mingmu Pill in Diabetic Retinopathy: An Integration of Serum Pharmacochemistry, Network Pharmacology, and Experimental Validation
The chemical components, blood-absorbed components, potential targets, and mechanistic pathways of SMP in DR treatment were systematically elucidated. This study preliminarily determined the material basis and pharmacological mechanisms of SMP, laying a foundation for further translational research and clinical application.
Authors
- Long Cheng (ORCID: https://orcid.org/0000-0002-8933-4730)
- Xiong Pi (ORCID: https://orcid.org/0000-0001-8835-6914)
- Junjie Hu (ORCID: https://orcid.org/0000-0002-1188-5399)
- Guoyan Mo
- Yan Meng (ORCID: https://orcid.org/0000-0003-3009-6800)
- Shiming Yang (ORCID: https://orcid.org/0000-0002-7808-2566)
- Tao Xiong (ORCID: https://orcid.org/0000-0002-9773-649X)
- Wei Jiang (ORCID: https://orcid.org/0000-0001-5469-5344)
- Zhaohua Shi (ORCID: https://orcid.org/0009-0003-1853-350X)
Institutions
- Hubei University of Chinese Medicine (CN)
- Huanggang Central Hospital (CN)
Publication Details
- Journal
- Phytochemical Analysis
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1002/pca.70038
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00