Global trends in prostate cancer burden among adults aged 80 years and older from 1990 to 2021 based on the global burden of disease 2021

While substantial global progress has been made in reducing PCa incidence, mortality, and DALYs among adults aged ≥ 80 years, significant disparities persist, especially in low-resource settings, mainly due to differences in detection, treatment, and risk reduction strategies. Ongoing efforts to promote equitable access to early detection, effective treatment, and risk factor mitigation are essential to further reduce the burden of PCa in the aging population worldwide.