The horse cardiac transcriptome: Moving towards a molecular understanding of atrial fibrillation
Persistent AF was associated with changes in metabolic and fibrotic pathways in the atria, with minimal ion channel remodeling. Targeting these pathways, rather than focusing solely on the electrical disturbance, may improve treatment outcomes in equine AF.
Authors
- Rasmus Kjøbsted (ORCID: https://orcid.org/0000-0002-0628-4994)
- Rikke Buhl (ORCID: https://orcid.org/0000-0002-8201-0186)
- Romain Barrès (ORCID: https://orcid.org/0000-0002-0158-519X)
- Charlotte Hopster‐Iversen (ORCID: https://orcid.org/0000-0003-3606-2484)
- Sarah Dalgas Nissen (ORCID: https://orcid.org/0000-0001-8598-7147)
- Kate M. Herum (ORCID: https://orcid.org/0000-0001-6617-6613)
- Thomas Jespersen (ORCID: https://orcid.org/0000-0001-6575-360X)
- Jørgen F. P. Wojtaszewski (ORCID: https://orcid.org/0000-0001-8185-3408)
- Simon Libak Haugaard (ORCID: https://orcid.org/0000-0003-1787-134X)
- Helena Carstensen (ORCID: https://orcid.org/0000-0001-8952-9637)
- Ali Altıntaş (ORCID: https://orcid.org/0000-0002-8932-0160)
- Jesper B. Birk (ORCID: https://orcid.org/0000-0001-9775-4789)
- Mélodie J. Schneider (ORCID: https://orcid.org/0000-0001-8739-8223)
Institutions
- University of Copenhagen (DK)
- Novo Nordisk (Denmark) (DK)
- Novo Nordisk Foundation (DK)
Publication Details
- Journal
- Equine Veterinary Journal
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1111/evj.70115
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00