Mechanistic insights into the inhibition of drug‐resistant cytomegalovirus by letermovir and ganciclovir

Despite different mechanisms of action, both drugs inhibited the spread of newly emerging resistant viruses around wild-type CMV-infected lesions during letermovir/ganciclovir treatment, suggesting the practical use of both drugs and strategies for treating drug-resistant CMV.

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Publication Details

Journal
British Journal of Pharmacology
Published
2025-11-14
DOI
https://doi.org/10.1111/bph.70239
Citations
1
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
1.35
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article

Mechanistic insights into the inhibition of drug‐resistant cytomegalovirus by letermovir and ganciclovir

Y Takemura, Kaoru Sakai, Tohru Daikoku, Noriaki Sato et al.
1 citations
British Journal of Pharmacology
Cytomegalovirus and herpesvirus research
1.35
article

Mechanistic insights into the inhibition of drug‐resistant cytomegalovirus by letermovir and ganciclovir

Y Takemura, Kaoru Sakai, Tohru Daikoku, Noriaki Sato, Atsuko Shiraki, Motoko Yanagita, Kazunari Tanabe, Kimiyasu Shiraki, Seiya Imoto, Masaya Takemoto
article en
1 citations

Abstract

Despite different mechanisms of action, both drugs inhibited the spread of newly emerging resistant viruses around wild-type CMV-infected lesions during letermovir/ganciclovir treatment, suggesting the practical use of both drugs and strategies for treating drug-resistant CMV.

British Journal of PharmacologyVol. 183(5)
Senri Kinran University (JP), Kyoto University (JP), Hokuriku Electric Power Company (Japan) (JP), Toyama City Hospital (JP), Chiba-Nishi General Hospital (JP), Toyama University Hospital (JP), Shonan Kamakura General Hospital (JP), Hokuriku University (JP), The University of Tokyo (JP)
Openalex Percentile: Top 14%
Cytomegalovirus and herpesvirus research
1.35
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