A glucose time in range of 70% attenuates the senescence-inducing and pro-inflammatory effects of hyperglycemia
A TIR above 70% is associated with attenuated pro-senescence and pro-inflammatory effects of hyperglycemia. These molecular results support the TIR target currently recommended by guidelines, especially for people with T1D.
Authors
- Klemen Dovč (ORCID: https://orcid.org/0000-0001-9201-2145)
- Valeria Pellegrini (ORCID: https://orcid.org/0009-0005-1187-5296)
- Francesco Prattichizzo (ORCID: https://orcid.org/0000-0002-2959-2658)
- Cesare Berra (ORCID: https://orcid.org/0000-0001-8431-8160)
- Rosalba La Grotta (ORCID: https://orcid.org/0000-0003-2224-4615)
- Antonio Ceriello (ORCID: https://orcid.org/0000-0001-8122-3203)
- Tadej Battelino (ORCID: https://orcid.org/0000-0002-0273-4732)
- Barbara Jenko Bizjan (ORCID: https://orcid.org/0000-0003-3452-7006)
- Francesca Carreras
- Karolina Mužina
Institutions
- University of Ljubljana (SI)
- Ljubljana University Medical Centre (SI)
- MultiMedica (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s12933-025-02983-3
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute