Inflammatory tropism in COVID-19: a comparative analysis of Delta and Omicron variants

While autoantibody levels remained normal, clinical profiles diverged significantly between variants. The Delta variant was associated with heightened systemic inflammation, whereas Omicron was associated with greater organ involvement, suggesting the possibility of distinct pathogenic mechanisms.

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Publication Details

Journal
BMC Immunology
Published
2025-11-14
DOI
https://doi.org/10.1186/s12865-025-00772-x
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Inflammatory tropism in COVID-19: a comparative analysis of Delta and Omicron variants

Ali Jandaghi, Afshin Samiei, Mahmood Khayatian, Narges Khaghanzadeh et al.
BMC Immunology
SARS-CoV-2 and COVID-19 Research
article

Inflammatory tropism in COVID-19: a comparative analysis of Delta and Omicron variants

Ali Jandaghi, Afshin Samiei, Mahmood Khayatian, Narges Khaghanzadeh, Mehdi Hassani Azad
article en

Abstract

While autoantibody levels remained normal, clinical profiles diverged significantly between variants. The Delta variant was associated with heightened systemic inflammation, whereas Omicron was associated with greater organ involvement, suggesting the possibility of distinct pathogenic mechanisms.

BMC ImmunologyVol. 26(1)
Hormozgan University of Medical Sciences (IR)
Openalex Percentile: Top 60%
SARS-CoV-2 and COVID-19 Research
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