Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum
Our study uncovered the stage-dependent dFC changes and their molecular underpinnings of brain network dysfunction across the ADS.
Authors
- Ning Zheng (ORCID: https://orcid.org/0000-0002-8114-553X)
- Wenzhen Zhu (ORCID: https://orcid.org/0000-0001-6252-9450)
- Yuanyuan Qin (ORCID: https://orcid.org/0000-0002-0673-3200)
- Su Yan (ORCID: https://orcid.org/0000-0003-3816-5065)
- Tian Tian (ORCID: https://orcid.org/0000-0003-0148-4900)
- Yuanhao Li (ORCID: https://orcid.org/0000-0002-6938-5012)
- Yan Shi
- Renpuchi Ci
Institutions
- Philips (Finland) (FI)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s13195-025-01898-1
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- National Natural Science Foundation of China