Molecular mechanisms by which C1orf112 promotes endometrial cancer progression and the development and validation of a clinical scoring model
Our findings highlight the potential clinical utility of C1orf112 as a diagnostic and prognostic biomarker in EC, and provide new insights into its regulatory molecular network. This study proposes a conceptual framework for understanding EC pathogenesis and guiding the development of targeted therapies. Nonetheless, further prospective clinical studies and mechanistic investigations are warranted to validate these findings.
Authors
- Xuan Meng (ORCID: https://orcid.org/0000-0003-2355-4068)
- Siling Ren (ORCID: https://orcid.org/0000-0002-2127-6941)
- Yiping Sun
- Yi Lan (ORCID: https://orcid.org/0000-0001-5501-1063)
- Liangdan Tang (ORCID: https://orcid.org/0000-0002-9500-6055)
- Lan Wang (ORCID: https://orcid.org/0000-0002-1564-6416)
Institutions
- Guilin Medical University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s13148-025-02003-x
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00