Risk Factors beyond Chemotherapy Exposure for Secondary Myeloid Neoplasms after Hematologic Cancers: A SEER-Based Study
Our study reveals population-level risk factors for sMNs, including novel links to autoimmune disease and G-CSF, in addition to known causes like chemotherapy/radiation. These findings underscore the complex pathogenesis of sMNs and the need for molecular data in prospective studies to guide prevention, detection, and survivorship care.
Authors
- Theresa Hahn
- Abhay Singh (ORCID: https://orcid.org/0000-0001-6657-8647)
- Rahul Mishra (ORCID: https://orcid.org/0000-0001-5631-1164)
- Swapna Thota (ORCID: https://orcid.org/0000-0002-4216-1414)
- Megan M. Herr (ORCID: https://orcid.org/0000-0001-5768-9396)
Institutions
- Roswell Park Comprehensive Cancer Center (US)
- Cleveland Clinic (US)
- University of Tennessee Health Science Center (US)
- Anne Arundel Medical Center (US)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1158/2767-9764.crc-25-0340
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- California Department of Public Health
- University of Southern California
- Centers for Disease Control and Prevention
- University of California, San Francisco
- National Cancer Institute