Severe myocardium suppression in two congenital heart disease patients after remdesivir use – a case report

Although causality cannot be proven, these cases highlight a potential risk of remdesivir-induced myocardial suppression in children with complex CHD and systemic inflammation. We recommend careful risk-benefit assessment and cautious use of remdesivir in patients with single-ventricle physiology or right ventricular failure, especially when treatment is initiated late in the disease course.