Long-term follow-up of patients with large segmental bone defects treated with 3D-printed polycaprolactone/tricalcium phosphate scaffolds
Reconstructive treatment of large bone defects remains challenging. The short-term follow-up of this treatment strategy showed promising results with progress in clinical and radiological follow-up. However, in this small cohort a lack of bone growth at the defect site was found in some of the cases that were clinically performing well. The use of PCL/TCP scaffolds remains a valuable treatment strategy in very large bone defects for retention and extension of the autologous bone and cells, though improvements in fixation, composition or structural properties could enhance their feasibility.
Authors
- Martijn van Griensven (ORCID: https://orcid.org/0000-0001-5104-9881)
- Taco Johan Blokhuis (ORCID: https://orcid.org/0000-0002-3601-3458)
- Martijn Poeze (ORCID: https://orcid.org/0000-0001-5005-1285)
- Lotte C. A. van der Broeck (ORCID: https://orcid.org/0009-0000-2006-5053)
- Maria Gabriella Fois (ORCID: https://orcid.org/0000-0001-9304-1554)
- Anna J. L. Lodewijks (ORCID: https://orcid.org/0000-0003-3091-4009)
- Carmen López-Iglesias (ORCID: https://orcid.org/0000-0002-9356-4109)
- Margot M.R. Warin
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- RWTH Aachen University (DE)
Publication Details
- Journal
- European Journal of Trauma and Emergency Surgery
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1007/s00068-025-02982-9
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universiteit Maastricht